• Product NameDacarbazine
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various Ys, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 4342-3-4
• Calculated MW 182.18
• Formulation C6H10N6O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN(C)N/N=C/1\C(=NC=N1)C(=O)N
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA polymerase beta
  Boling pt:456.3C
  Melting pt:199-205C
  Solubility:DMSO: 3 mg/mL (16.46 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lonn U, Lohn S. Y Res. 1987 Jan 1;47(1):26-30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting