• Product Name(S)-(+)-Camptothecin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAn alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
• Target NameTopoisomerase inhibitor
• CAS No. 7689-3-4
• Calculated MW 348.36
• Formulation C20H16N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo I
  Boling pt:
  Melting pt:
  Solubility:DMSO: 3 mg/mL (8.61 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Teicher BA. Biochem Pharmacol. 2007 Oct 22;.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting