• Product NameDiminazene Aceturate
• Brief DescriptionInhibitors
• Purification95.00%
• Biological ActivityDiminazene, also known as Diminazine, 4,4-(Diazoamino)benzamidine, 4,4-(1-Triazene-1,3-diyl)bis-benzenecarboximidamide, Diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a solid. This compound belongs to the phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent attached to a phenyl group. Known drug targets of diminazene include HTH-type transcriptional regulator QacR, trypsin-1, amiloride-sensitive amine oxidase [copper-containing], and mitochondrial peroxiredoxin-5.
• Target NameOthers; Serine Protease
• CAS No. 908-54-3
• Calculated MW 515.52
• Formulation C22H29N9O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:NC(=N)C1=CC=C(N\N=N\C2=CC=C(C=C2)C(N)=N)C=C1
  Pathways:Others; Proteases/Proteasome
  Receptor:Peroxiredoxin-5; QacR; Trypsin-1
  Boling pt:463.3C?
  Melting pt:
  Solubility:Water: 100 mg/mL (193.97 mM); DMSO: 19 mg/mL (36.85 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Overington JP, et al. Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting