• Product NameRifaximin
• Brief DescriptionInhibitors
• Purification99.56%
• Biological ActivityRifaximin(Xifaxan), an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis and bacterial cell growth. As rifaximin is not well absorbed, its antibacterial activity is largely localized to the gastrointestinal tract.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 80621-81-4
• Calculated MW 785.88
• Formulation C43H51N3O11
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C[C@H]1/C=C/C=C(\C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)/C
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA/RNA Synthesis
  Boling pt:
  Melting pt:200-205C
  Solubility:Ethanol: 3 mg/mL (3.81 mM); DMSO: 47 mg/mL (59.8 mM)
  Appearance:Red Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cheng J, et al. J Pharmacol Exp Ther. 2010 Jul 13.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting