• Product NameTiotropium bromide
• Brief DescriptionInhibitors
• Purification96.82%
• Biological ActivityTiotropium is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.
• Target NameAChR antagonist
• CAS No. 136310-93-5
• Calculated MW 472.42
• Formulation C19H22BrNO4S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:C[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)C(C4=CC=CS4)(C5=CC=CS5)O)C.[Br-]
  Pathways:Neuroscience
  Receptor:mAChR
  Boling pt:
  Melting pt:218-220C
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hansel TT, Barnes PJ. Drugs Today (Barc). 2002 Sep;38(9):585-600.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting