• Product NameTetracaine hydrochloride
• Brief DescriptionInhibitors
• Purification99.28%
• Biological ActivityTetracaine hydrochloride (Pontocaine) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. Tetracaine hydrochloride (Pontocaine) is used to block temporarily the pain "message" that is sent along the nerves that connect the eyes to the brain. Tetracaine hydrochloride (Pontocaine) is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
• Target NameSodium Channel inhibitor
• CAS No. 136-47-0
• Calculated MW 300.83
• Formulation C15H24N2O2HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:Cl.CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C
  Pathways:Membrane transporter/Ion channel
  Receptor:Sodium Channel
  Boling pt:389.4C?
  Melting pt:149C
  Solubility:Ethanol: 30 mg/mL (99.72 mM); Water: 60 mg/mL (199.45 mM); DMSO: 60 mg/mL (199.45 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Leng T, et al. Mol Pain. 2013 Jun 10;9:27

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting