• Product NameNicardipine hydrochloride
• Brief DescriptionInhibitors
• Purification99.89%
• Biological ActivityNicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
• Target NameAChR antagonist; Adrenergic Receptor antagonist; Calcium Channel inhibitor
• CAS No. 54527-84-3
• Calculated MW 515.99
• Formulation C26H30ClN3O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:Cl.COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1
  Pathways:Neuroscience; Membrane transporter/Ion channel; GPCR/G Protein
  Receptor:mAChR; Adrenergic Receptor; Calcium Channel
  Boling pt:603.4C
  Melting pt:176-178C
  Solubility:DMSO: 100 mg/mL (193.8 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Willis AL, et al. Arteriosclerosis, 1985, 5(3), 250-255.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting