• Product NamePyrilamine maleate
• Brief DescriptionInhibitors
• Purification99.71%
• Biological ActivityA histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
• Target NameHistamine Receptor antagonist
• CAS No. 59-33-6
• Calculated MW 401.47
• Formulation C21H27N3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:423.8C
  Melting pt:100-101C
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Moriyama K, et al. Inflamm Res. 2009 Dec;58(12):873-80.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting