• Product NameAzathioprine
• Brief DescriptionInhibitors
• Purification99.25%
• Biological ActivityAzathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.
• Target NameGPR inhibitor; Rho inhibitor
• CAS No. 446-86-6
• Calculated MW 277.26
• Formulation C9H7N7O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
  Pathways:Cell Cycle/Checkpoint; Endocrinology/Hormones
  Receptor:HGPRT; Rac1
  Boling pt:685.7C
  Melting pt:243-244C
  Solubility:DMSO: 54 mg/mL (194.76 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tiede I, et al. J Clin Invest, 2003, 111(8), 1133-1145.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting