• Product NameAlvimopan
• Brief DescriptionInhibitors
• Purification99.78%
• Biological ActivityAlvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.
• Target NameOpioid Receptor antagonist
• CAS No. 156053-89-3
• Calculated MW 424.53
• Formulation C25H32N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:C[C@H]1CN(CC[C@@]1(C)C2=CC(=CC=C2)O)C[C@H](CC3=CC=CC=C3)C(=O)NCC(=O)O
  Pathways:Endocrinology/Hormones; GPCR/G Protein; Neuroscience
  Receptor:μ-opioid receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cassel JA, et al. Eur J Pharmacol. 2005 Sep 27;520(1-3):29-36.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting