• Product NameNabumetone
• Brief DescriptionInhibitors
• Purification99.61%
• Biological ActivityNabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.
• Target NameCOX inhibitor; MPO inhibitor
• CAS No. 42924-53-8
• Calculated MW 228.29
• Formulation C15H16O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:COC1=CC2=C(C=C1)C=C(CCC(C)=O)C=C2
  Pathways:Immunology/Inflammation; Metabolism; Neuroscience
  Receptor:COX-1; COX-2; MPO
  Boling pt:371.1C?
  Melting pt:80-81C
  Solubility:Ethanol: 25 mg/mL (109.5 mM); DMSO: 46 mg/mL (201.49 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hedner T, et al. Drugs, 2004, 64(20), 2315-2343.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting