• Product NameVincristine sulfate
• Brief DescriptionInhibitors
• Purification98.82%
• Biological ActivityVincristine (sulfate) is an inhibitor of polymerization of microtubules by binding to tubulin with IC50?of 32 μM.
• Target NameMicrotubule Associated inhibitor
• CAS No. 2068-78-2
• Calculated MW 923.04
• Formulation C46H58N4O14S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
  Pathways:Cytoskeletal Signaling
  Receptor:microtubule
  Boling pt:273-281C
  Melting pt:300C
  Solubility:Water: 60 mg/mL (65.0 mM); DMSO: 100 mg/mL (108.33 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Jordan MA, et al. Y Res, 1985, 45(6), 2741-2747.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting