• Product NameDiacerein
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDiacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.
• Target NameIL Receptor inhibitor
• CAS No. 13739-02-1
• Calculated MW 368.29
• Formulation C19H12O8
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CC(=O)OC1=CC=CC2=C1C(=O)C1=C(OC(C)=O)C=C(C=C1C2=O)C(O)=O
  Pathways:Immunology/Inflammation
  Receptor:IL-1β
  Boling pt:
  Melting pt:217-218C
  Solubility:DMSO: 48 mg/mL (130.33 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yaron M, et al. Osteoarthritis Cartilage, 1999, 7(3), 272-280.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting