• Product NameNepafenac
• Brief DescriptionInhibitors
• Purification99.88%
• Biological ActivityNepafenac(AHR 9434; AL 6515; Nevanac) is a selective COX-2 inhibitor; is prodrug of Amfenac.
• Target NameCOX inhibitor
• CAS No. 78281-72-8
• Calculated MW 254.28
• Formulation C15H14N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N
  Pathways:Immunology/Inflammation; Neuroscience
  Receptor:COX-1; COX-2
  Boling pt:562.5C?
  Melting pt:177-181C
  Solubility:DMSO: 50 mg/mL (196.63 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gamache DA, et al. Inflammation. 2000 Aug;24(4):357-70.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting