• Product NameTTNPB (Arotinoid Acid)
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTTNPB (Arotinoid Acid; AGN191183; Ro 13-7410)is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.
• Target NameRetinoid Receptor agonist
• CAS No. 71441-28-6
• Calculated MW 348.48
• Formulation C24H28O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C/C(=C\C1=CC=C(C=C1)C(=O)O)/C2=CC3=C(C=C2)C(CCC3(C)C)(C)C
  Pathways:Metabolism
  Receptor:RARα; RARβ; RARγ; RARγ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 15 mg/mL warmed (43.04 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pignatello MA, et al. Toxicol Appl Pharmacol. 1997, 142(2), 319-327.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting