• Product NameCisapride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system.
• Target Name5-HT Receptor antagonist; Potassium Channel inhibitor
• CAS No. 81098-60-4
• Calculated MW 465.95
• Formulation C23H29ClFN3O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:COC1CN(CCCOC2=CC=C(F)C=C2)CCC1NC(=O)C1=CC(Cl)=C(N)C=C1OC
  Pathways:GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
  Receptor:5-HT; Potassium Channel
  Boling pt:
  Melting pt:
  Solubility:Water: 2.71 mg/L.
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nagakura Y, et al. Pharmacol Res. 1999 May;39(5):375-82.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting