• Product NameNorfloxacin
• Brief DescriptionInhibitors
• Purification99.83%
• Biological ActivityNorfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell division. This mechanism can also affect mammalian cell replication
• Target NameDNA gyrase inhibitor; Topoisomerase inhibitor
• CAS No. 70458-96-7
• Calculated MW 319.34
• Formulation C16H18FN3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(C=C12)N1CCNCC1
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA gyrase; Topo II
  Boling pt:
  Melting pt:
  Solubility:Ethanol: <1 mg/mL (<1 mM); Water: <1 mg/mL (<1 mM); DMSO: <1 mg/mL (<1 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Preissner S, et al. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting