• Product NamePropylthiouracil
• Brief DescriptionInhibitors
• Purification99.94%
• Biological ActivityPropylthiouracil is a Thyroid Hormone Synthesis Inhibitor. A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
• Target NameThyroid hormone receptor(THR) inhibitor
• CAS No. 51-52-5
• Calculated MW 170.24
• Formulation C7H10N2OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CCCC1=CC(=O)NC(=S)N1
  Pathways:Endocrinology/Hormones
  Receptor:Thyroid peripheral conversion
  Boling pt:355.2C?
  Melting pt:218-220C
  Solubility:Ethanol: 19 mg/mL (111.61 mM); DMSO: 34 mg/mL (199.72 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sugawara M, et al. Thyroid. 1999 May;9(5):513-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting