• Product NameDisopyramide
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
• Target NameAChR antagonist; Potassium Channel inhibitor; Sodium Channel inhibitor
• CAS No. 3737-9-5
• Calculated MW 339.47
• Formulation C21H29N3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:Cl.COC1=C(O)C=CC(CN)=C1
  Pathways:Membrane transporter/Ion channel; Neuroscience
  Receptor:mAChR; Potassium Channel; Sodium Channel
  Boling pt:505.2C
  Melting pt:94.5-950C
  Solubility:Water: 44.9 mg/L
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sugao M, et al. J Cardiovasc Pharmacol. 2005 Jun;45(6):545-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting