• Product NameAmlodipine
• Brief DescriptionInhibitors
• Purification99.83%
• Biological ActivityAmlodipine is a long-acting calcium channel blocker. Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells.
• Target NameCalcium Channel inhibitor
• CAS No. 88150-42-9
• Calculated MW 408.88
• Formulation C20H25ClN2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:OS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
  Pathways:Membrane transporter/Ion channel
  Receptor:Calcium Channel
  Boling pt:
  Melting pt:178-179C
  Solubility:Ethanol: 82 mg/mL (200.54 mM); DMSO: 82 mg/mL (200.54 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhang X, et al. Circulation, 1998, 97(6), 576-580.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting