• Product NameLoxapine succinate salt
• Brief DescriptionInhibitors
• Purification99.92%
• Biological ActivityLoxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.
• Target Name5-HT Receptor antagonist; Dopamine Receptor antagonist
• CAS No. 27833-64-3
• Calculated MW 445.9
• Formulation C22H24ClN3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT2 (bovine); 5-HT2 (bovine); 5-HT2 (human); D2; D4
  Boling pt:
  Melting pt:150-152C
  Solubility:Ethanol: 2 mg/mL (4.48 mM); DMSO: 89 mg/mL (199.59 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Bhardwaj RM, et al. Acta Crystallogr C. 2013 Nov; 69(Pt 11):1273-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting