• Product NameMesna
• Brief DescriptionInhibitors
• Purification99.93%
• Biological ActivityMesna(Uromitexan, Mesnex), a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion.
• Target NameOthers
• CAS No. 19767-45-4
• Calculated MW 164.18
• Formulation C2H5NaO3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:[Na+].[O-]S(=O)(=O)CCS
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:>240C?
  Solubility:Water: 7 mg/mL (42.63 mM); DMSO: 33 mg/mL (200.99 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kalcioglu MT, et al. Am J Otolaryngol. 2014 May-Jun;35(3):357-61.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting