• Product NameGemfibrozil
• Brief DescriptionInhibitors
• Purification99.90%
• Biological ActivityGemfibrozil (Lopid) is an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. Increases activity of Peroxisome proliferator-activated receptor-alpha (PPARα) 'transcription factor ligand' , a receptor that is involved in metabolism of carbohydrates and fats, as well as adipose tissue differentiation. This increase in the synthesis of lipoprotein lipase thereby increases the clearance of triglycerides.
• Target NamePPAR agonist
• CAS No. 25812-30-0
• Calculated MW 250.33
• Formulation C15H22O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
  Pathways:Metabolism
  Receptor:PPARα
  Boling pt:158-159C
  Melting pt:61-63C
  Solubility:Ethanol: 50 mg/mL (199.73 mM); DMSO: 50 mg/mL (199.73 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Clavey V, et al. Cell Physiol Biochem. 1999;9(3):139-49.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting