• Product NamePemirolast potassium
• Brief DescriptionInhibitors
• Purification98.91%
• Biological ActivityPemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis. Pemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel.
• Target NameHistamine Receptor antagonist
• CAS No. 100299-08-9
• Calculated MW 266.31
• Formulation C10H7KN6O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Respiratory system
  SMILES:CC1=CC=CN2C(=O)C(=CN=C12)C1=NNN=N1
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:
  Melting pt:310-311C?
  Solubility:Water: 53 mg/mL (199.02 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kemp JP, et al. Ann Allergy, 1992, 68(6), 488-491.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting