• Product NameTrifluridine
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTrifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase. TFT also inhibits thymidylate synthase (TS), a rate-limiting enzyme of DNA biosynthesis, and is incorporated into DNA.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 70-00-8
• Calculated MW 296.2
• Formulation C10H11F3N2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA/RNA Synthesis; Thymidylate synthase
  Boling pt:
  Melting pt:190-193C
  Solubility:Ethanol: 59 mg/mL (199.18 mM); Water: 59 mg/mL (199.18 mM); DMSO: 59 mg/mL (199.18 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shintani M, et al. Oncol Rep. 2010 May; 23(5):1345-50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting