• Product NamePhenylbutazone
• Brief DescriptionInhibitors
• Purification99.92%
• Biological ActivityPhenylbutazone(Butazolidin, Butatron) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis. Its use is limited by such severe side effects as suppression of white blood cell production and aplastic anemia.
• Target NameCOX inhibitor
• CAS No. 50-33-9
• Calculated MW 308.38
• Formulation C19H20N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CCCCC1C(=O)N(N(C1=O)C1=CC=CC=C1)C1=CC=CC=C1
  Pathways:Immunology/Inflammation; Neuroscience
  Receptor:COX
  Boling pt:424.9C?
  Melting pt:104-107C
  Solubility:Ethanol: 62 mg/mL (201.05 mM); DMSO: 62 mg/mL (201.05 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Arifah AK, Lees P. J Vet Pharmacol Ther. 2002 Aug;25(4):299-309.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting