• Product NameDoxorubicin
• Brief DescriptionInhibitors
• Purification99.37%
• Biological ActivityDoxorubicin is an Anthracycline Topoisomerase Inhibitor. The mechanism of action of doxorubicin is as a Topoisomerase Inhibitor. The chemical classification of doxorubicin is Anthracyclines.
• Target NameTopoisomerase inhibitor
• CAS No. 23214-92-8
• Calculated MW 543.52
• Formulation C27H29NO11
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo II
  Boling pt:
  Melting pt:205-208C
  Solubility:DMSO: 10 mM
  Appearance:Orange Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Preissner S, et al. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting