• Product NameCisatracurium besylate
• Brief DescriptionInhibitors
• Purification99.57%
• Biological ActivityCisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium Besylate acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine. The neuromuscular block produced by cisatracurium besylate is readily antagonized by anticholinesterase agents once recovery has started. As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at the time of reversal, the longer the time required for recovery of neuromuscular function. Compared to other neuromuscular blocking agents, it is intermediate in its onset and duration of action.
• Target NameAChR antagonist; Adrenergic Receptor antagonist
• CAS No. 96946-42-8
• Calculated MW 1243.48
• Formulation C53H72N2O122C6H5O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:C[N@@+]1(CCC2=CC(=C(C=C2[C@H]1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N@+]4(CCC5=CC(=C(C=C5[C@H]4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]
  Pathways:Neuroscience; GPCR/G Protein
  Receptor:AChR; Adrenergic Receptor
  Boling pt:
  Melting pt:90-93C
  Solubility:Ethanol: 249 mg/mL (200.24 mM); Water: 47 mg/mL (37.79 mM); DMSO: 249 mg/mL (200.24 mM)
  Appearance:Liquid
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Dieye E, et al. Ann Intensive Care. 2014 Feb 11;4(1):3.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting