• Product NameRamelteon
• Brief DescriptionInhibitors
• Purification97.21%
• Biological ActivityRamelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
• Target NameMMP agonist
• CAS No. 196597-26-9
• Calculated MW 259.35
• Formulation C16H21NO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CCC(=O)NCC[C@@H]1CCC2=C1C3=C(C=C2)OCC3
  Pathways:Proteases/Proteasome
  Receptor:MT receptor (chicken); MT1 receptor; MT2 receptor
  Boling pt:455.3C
  Melting pt:113-115C
  Solubility:Ethanol: 52 mg/mL (200.5 mM); DMSO: 52 mg/mL (200.5 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kato K, et al. Neuropharmacology. 2005 Feb;48(2):301-10.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting