• Product NameTrilostane
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityTrilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994.
• Target NameDehydrogenase inhibitor
• CAS No. 13647-35-3
• Calculated MW 329.43
• Formulation C20H27NO3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC[C@]45[C@@]3(CC(=C([C@H]4O5)O)C#N)C
  Pathways:Metabolism
  Receptor:3 β-hydroxysteroid dehydrogenase
  Boling pt:516.5C
  Melting pt:264C
  Solubility:DMSO: 65 mg/mL (197.31 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Puddefoot JR, et al. Expert Opin PharmacOthers. 2006 Dec;7(17):2413-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting