• Product NameAliskiren hemifumarate
• Brief DescriptionInhibitors
• Purification96.18%
• Biological ActivityAliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM.
• Target NameRAAS inhibitor
• CAS No. 173334-58-2
• Calculated MW 1219.6
• Formulation C30H53N3O61/2C4H4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=C/C(=O)O)\C(=O)O
  Pathways:Endocrinology/Hormones
  Receptor:Renin
  Boling pt:
  Melting pt:72-75C
  Solubility:Ethanol: 100 mg/mL (163.98 mM); Water: 100 mg/mL (163.98 mM); DMSO: 100 mg/mL (163.98 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nakamura Y, et al. ACS Med Chem Lett, 2012, 3(9), 754C758.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting