• Product NameRapamycin (Sirolimus)
• Brief DescriptionInhibitors
• Purification98.73%
• Biological ActivitySirolimus is a mTOR Inhibitor Immunosuppressant.
• Target NamemTOR inhibitor
• CAS No. 53123-88-9
• Calculated MW 914.18
• Formulation C51H79NO13
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:mTOR
  Boling pt:973.02C
  Melting pt:183-185C
  Solubility:DMSO: 20 mg/mL (21.87 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Dowling RJ, et al. Biochim Biophys Acta. 2010 Mar;1804(3):433-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting