• Product NamePirenzepine dihydrochloride
• Brief DescriptionInhibitors
• Purification99.88%
• Biological ActivityAn antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
• Target NameAChR antagonist
• CAS No. 29868-97-1
• Calculated MW 424.32
• Formulation C19H21N5O22HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:Cl.Cl.CN1CCN(CC(=O)N2C3=CC=CC=C3C(=O)NC3=C2N=CC=C3)CC1
  Pathways:Neuroscience
  Receptor:mAChR
  Boling pt:541.7C
  Melting pt:248-250C
  Solubility:Water: 100 mM
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chen X, et al. Nucleic Acids Res. 2002 Jan 1; 30(1):412-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting