• Product NameNifuroxazide
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityNifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity .
• Target NameSTAT inhibitor
• CAS No. 965-52-6
• Calculated MW 275.22
• Formulation C12H9N3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C1=CC(=CC=C1C(=O)N/N=C/C2=CC=C(O2)[N+](=O)[O-])O
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT1; STAT3; STAT5
  Boling pt:
  Melting pt:281-283C
  Solubility:DMSO: 55 mg/mL (199.84 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nelson EA, et al. Blood, 2008, 112(13), 5095-5102.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting