• Product NameDeferidone
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDeferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired. FDA approved on October 14, 2011.
• Target NameOthers; UGT inhibitor
• CAS No. 30652-11-0
• Calculated MW 139.15
• Formulation C7H9NO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN1C=CC(=O)C(O)=C1C
  Pathways:Metabolism; Others
  Receptor:iron; UGT1-6
  Boling pt:232.7C?
  Melting pt:272-275C
  Solubility:Water: 1 mg/mL (7.18 mM)
  Appearance:White Needle Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Barnab N, et al. Free Radic Biol Med, 2002, 33(2), 266-275.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting