• Product NameTigecycline
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityTigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.
• Target Nameribosome inhibitor
• CAS No. 220620-09-7
• Calculated MW 585.65
• Formulation C29H39N5O8
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC(C)(C)NCC(=O)NC1=C(C2=C(C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C2O)O)O)C(=O)N)N(C)C)C(=C1)N(C)C)O
  Pathways:Microbiology&virology
  Receptor:30S ribosome
  Boling pt:890.92C
  Melting pt:164-166C
  Solubility:Water: 100 mg/mL (170.75 mM); DMSO: 100 mg/mL (170.75 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Livermore DM, et al. J Antimicrob ChemOthers, 2005, 56(4), 611-614.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting