• Product NameTelmisartan
• Brief DescriptionInhibitors
• Purification99.96%
• Biological ActivityTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
• Target NameRAAS inhibitor
• CAS No. 144701-48-4
• Calculated MW 514.62
• Formulation C33H30N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCCC1=NC2=C(C)C=C(C=C2N1CC1=CC=C(C=C1)C1=CC=CC=C1C(O)=O)C1=NC2=CC=CC=C2N1C
  Pathways:Endocrinology/Hormones
  Receptor:angiotensin II type 1 receptor
  Boling pt:771.9C?
  Melting pt:261-263C
  Solubility:DMSO: 13 mg/mL (25.26 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Benson SC, et al. Hypertension, 2004, 43(5), 993-1002.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting