• Product NameDesvenlafaxine
• Brief DescriptionInhibitors
• Purification99.46%
• Biological ActivityDesvenlafaxine (O-desmethylvenlafaxine) the major active metabolite of venlafaxine, is an antidepressant from the serotonin-norepinephrine reuptake inhibitor (SNRI class). Desvenlafaxine may be used to treat major depressive disorder and is being studied for use in the management of vasomotor symptoms in postmenopausal women. It is formulated as an extended release tablet. FDA approved in 2008.
• Target Name5-HT Receptor inhibitor; Norepinephrine inhibitor
• CAS No. 93413-62-8
• Calculated MW 263.38
• Formulation C16H25NO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN(C)CC(C1=CC=C(O)C=C1)C1(O)CCCCC1
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT; Norepinephrine (NE)
  Boling pt:403.8C?
  Melting pt:208-213C
  Solubility:Ethanol: 3 mg/mL (11.39 mM); DMSO: 37 mg/mL (140.48 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Deecher DC, et al. J Pharmacol Exp Ther. 2006 Aug;318(2):657-65.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting