• Product NameLetrozole
• Brief DescriptionInhibitors
• Purification99.68%
• Biological ActivityLetrozole (INN, trade name Femara) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast Y Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme.
• Target NameAromatase inhibitor
• CAS No. 112809-51-5
• Calculated MW 285.3
• Formulation C17H11N5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:N#CC1=CC=C(C=C1)C(N1C=NC=N1)C1=CC=C(C=C1)C#N
  Pathways:Endocrinology/Hormones
  Receptor:Aromatase
  Boling pt:374.4C
  Melting pt:181-183C
  Solubility:DMSO: 57 mg/mL (199.78 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Haynes BP, et al. J Steroid Biochem Mol Biol, 2003, 87(1), 35-45.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting