• Product NameValerin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityValproic acid is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
• Target NameGABA Receptor inhibitor; HDAC inhibitor
• CAS No. 1069-66-5
• Calculated MW 166.2
• Formulation C8H15NaO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:[Na+].CCCC(CCC)C([O-])=O
  Pathways:Chromatin/Epigenetic; Membrane transporter/Ion channel; DNA Damage/DNA Repair; Neuroscience; NF-κb
  Receptor:GABAR; HDAC2; HDAC9
  Boling pt:220C
  Melting pt:300C
  Solubility:Ethanol: 33 mg/mL (198.56 mM); Water: 33 mg/mL (198.56 mM); DMSO: 33 mg/mL (198.56 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kramer OH, et al. EMBO J. 2003 Jul 1; 22(13): 3411-20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting