• Product NameIsotretinoin
• Brief DescriptionInhibitors
• Purification98.06%
• Biological ActivityIsotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain Y, pancreatic Y and more.
• Target NameRetinoid Receptor inhibitor
• CAS No. 4759-48-2
• Calculated MW 300.44
• Formulation C20H28O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
  Pathways:Metabolism
  Receptor:RAR
  Boling pt:
  Melting pt:172-175C
  Solubility:Ethanol: 1 mg/mL warmed (3.32 mM); DMSO: 60 mg/mL (199.7 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Webster WS, et al. J Craniofac Genet Dev Biol, 1986, 6(3), 211-222.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting