• Product NameGlyburide
• Brief DescriptionInhibitors
• Purification99.77%
• Biological ActivityGlibenclamide(Glyburide) is a sulfonylurea compound that modulates insulin production.
• Target NamePotassium Channel inhibitor
• CAS No. 10238-21-8
• Calculated MW 494.01
• Formulation C23H28ClN3O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
  Pathways:Membrane transporter/Ion channel
  Receptor:Bile salt export pump; Potassium Channel
  Boling pt:
  Melting pt:168-173C
  Solubility:DMSO: 99mg/ml(200.4 mM);Water: <1mg/ml;Ethanol: <1mg/ml
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pondugula SR, et al. Physiol Genomics. 2006 Jan 12;24(2):114-23.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting