• Product NameParoxetine hydrochloride
• Brief DescriptionInhibitors
• Purification99.61%
• Biological ActivityParoxetine Hydrochloride is an antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs) and has GRK2 inhibitory ability with IC50 of 14 μM.
• Target Name5-HT Receptor antagonist; AChR inhibitor; GRK inhibitor
• CAS No. 78246-49-8
• Calculated MW 365.83
• Formulation C19H21CIFNO3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT; AChR; GRK2
  Boling pt:
  Melting pt:129-131C
  Solubility:Ethanol: 35 mg/mL (95.67 mM); Water: 10 mg/mL (27.33 mM); DMSO: 73 mg/mL (199.54 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Le Poul E, et al. Naunyn Schmiedebergs Arch Pharmacol, 1995, 352(2), 141-148.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting