• Product NameAmlexanox
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAmlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1C2 μM.
• Target NameFGFR inhibitor; IL Receptor antagonist; Others inhibitor
• CAS No. 68302-57-8
• Calculated MW 298.29
• Formulation C16H14N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Respiratory system
  SMILES:CC(C)C1=CC2=C(OC3=NC(N)=C(C=C3C2=O)C(O)=O)C=C1
  Pathways:Angiogenesis; Immunology/Inflammation; Others; Tyrosine Kinase/Adaptors
  Receptor:FGFR1; IL-3; Protein S100-P
  Boling pt:
  Melting pt:>300C
  Solubility:DMSO: 100 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shishibori T, et al. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting