• Product NameChlorzoxazone
• Brief DescriptionInhibitors
• Purification99.72%
• Biological ActivityChlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to quantify cytochrome P450 2E1 (CYP2E1) activity in humans.
• Target NamePotassium Channel inhibitor
• CAS No. 95-25-0
• Calculated MW 169.57
• Formulation C7H4ClNO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:ClC1=CC2=C(OC(=O)N2)C=C1
  Pathways:Membrane transporter/Ion channel
  Receptor:Potassium Channel
  Boling pt:191-192C
  Melting pt:
  Solubility:Ethanol: 34 mg/mL (200.5 mM); DMSO: 34 mg/mL (200.5 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Dong DL, et al. Eur J Pharmacol. 2006 Sep 18;545(2-3):161-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting