• Product NameRosuvastatin
• Brief DescriptionInhibitors
• Purification99.75%
• Biological ActivityRosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reducuase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Rosuvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
• Target NameHMG-CoA Reductase inhibitor
• CAS No. 287714-41-4
• Calculated MW 481.54
• Formulation C22H28FN3O6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C
  Pathways:Metabolism
  Receptor:HMG-CoA reductase
  Boling pt:
  Melting pt:
  Solubility:Sparingly soluble in Water
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Watanabe M, et al. Bioorg Med Chem, 1997, 5(2), 437-444.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting