• Product NameTolazoline hydrochloride
• Brief DescriptionInhibitors
• Purification99.85%
• Biological ActivityTolazoline hydrochloride is a vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
• Target NameAdrenergic Receptor antagonist
• CAS No. 59-97-2
• Calculated MW 196.68
• Formulation C10H13ClN2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Cl.C(C1=NCCN1)C1=CC=CC=C1
  Pathways:GPCR/G Protein
  Receptor:α-adrenergic receptor
  Boling pt:
  Melting pt:172-176C
  Solubility:Ethanol: 39 mg/mL (198.29 mM); Water: 39 mg/mL (198.29 mM); DMSO: 39 mg/mL (198.29 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lei L, et al. J Cardiovasc Pharmacol, 1998, 31(5), 721-733.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting