• Product NameMethylisobutylxanthine
• Brief DescriptionInhibitors
• Purification98.00%
• Biological Activity3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
• Target NamePDE inhibitor
• CAS No. 28822-58-4
• Calculated MW 222.24
• Formulation C10H14N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O
  Pathways:Metabolism
  Receptor:PDE3; PDE4; PDE5
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Jin KS, et al. Food Chem Toxicol. 2014 Jun;68:38-43.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting