• Product NameSCR7 pyrazine
• Brief DescriptionInhibitors
• Purification99.85%
• Biological ActivitySCR7 is a specific DNA Ligase IV inhibitor, which blocks nonhomologous end-joining (NHEJ).
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 14892-97-8
• Calculated MW 332.38
• Formulation C18H12N4OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:O=C1NC(=S)NC2=C1N=C(C1=CC=CC=C1)C(=N2)C1=CC=CC=C1
  Pathways:DNA Damage/DNA Repair
  Receptor:DNALigase IV
  Boling pt:
  Melting pt:
  Solubility:DMSO: 66 mg/mL (198.56 mM)
  Appearance:YellowPowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Srivastava M, et al. Cell. 2012, 151(7), 1474-1487.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting