• Product NameNPS 2143
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityNPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor.
• Target NameCalcium Channel antagonist
• CAS No. 284035-33-2
• Calculated MW 408.92
• Formulation C24H25ClN2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O
  Pathways:Membrane transporter/Ion channel
  Receptor:Ca(2+) receptor
  Boling pt:
  Melting pt:145-147
  Solubility:DMSO: 82 mg/mL (200.52 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nemeth EF, et al. J Pharmacol Exp Ther. 2001, 299(1), 323-331.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting